With a very innovative portfolio of molecular tests at some of the most affordable prices and the fastest turnaround times in the world, we have got quite a good share of interest in our tests from outside India. One of the
“I felt dizzy as I felt the ground give way under my feet. I was playing badminton early on a Saturday. I gently hopped to the nearest chair. After going through the rigmarole of MRI it was diagnosed with a
Diuretics: Personalized medicine Diuretics are often the first line of treatment for hypertension, but their effectiveness in terms of BP (blood pressure) lowering is inconsistent. The NEDD4L gene has a strong pharmacogenetic effect on the efficacy of thiazide diuretics. It
Warfarin: Personalized medicine Warfarin (coumarin), acenocoumarol and phenprocoumon are vitamin K antagonist (VKA) anticoagulants used in patients with deep vein thrombosis, thromboembolism, cardiovascular or cerebrovascular risk, or after surgery. It has a very narrow therapeutic index and causes severe adverse
Statins: Personalized medicine Despite the benefits of statin treatment in lowering cholesterol, statin-related adverse effects including myalgia and myopathy have been widely reported in patients. The incidence of muscle complaints in patients using statins is 9-20% in an outpatient setting.
Female infertility: FSH and personalized medicine Follicle stimulating hormone (FSH) is responsible for the growth and recruitment of immature ovarian follicles in women. It acts by binding to the FSH receptor (FSHR) present on ovarian and uterine cells. A common
Male infertility: FSH and Personalized medicine Men with infertility and where both partners are infertile will benefit from this test. It genotypes the patient for these two variations in FSHR and FSHB and classifies him for infertility treatment by FSH administration. The report will indicate recommendations for improving
SERPINE1 in Thrombophilia SERPINE1 gene encodes plasminogen activator inhibitor type 1 (PAI-1) and inhibits fibrinolysis, or clot dissolution. The 4G variant results in increased expression of SERPINE1 and consequently higher inhibition of fibrinolysis, thus leading to thrombophilia. Below are verbatim