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SERPINE1 in Thrombophilia SERPINE1 gene encodes plasminogen activator inhibitor type 1 (PAI-1) and inhibits fibrinolysis, or clot dissolution. The 4G variant results in increased expression of SERPINE1 and consequently higher inhibition of fibrinolysis, thus leading to thrombophilia. Below are verbatim
Heart Attack and Stroke Risk: Thrombophilia Blood clotting is regulated by your genes. Some people have a high propensity of clotting which can lead to high risk of developing heart attack, stroke, pulmonary embolism, or venous thrombosis. This test is
...INTRO LINES... Thrombophilia, or hypercoagulability, is the increased tendency of blood to clot These genetic mutations can cause heart attack or stroke in the absence of conventional risk factors Cardio/Cerebrovascular disease Myocardial infarction (heart attacks) and strokes are seen in
...INTRO LINES... Improve success rates in case of pregnancy complications If case of recurrent miscarriages (abortions), preeclampsia or Intrauterine growth restriction (IUGR), this test can help you. Abortion, miscarriage, preeclampsia, IUGR 15-60% of all recurrent miscarriages are due to thrombophilia,
