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So far sooraj@swagene has created 53 blog entries.

The Story of Swagene – Part I

This is an email interview with the Founders of Swagene that will be published over two parts. Introducing Swagene: Could you tell us something about your venture? Swagene is an expert molecular diagnostic lab that pioneers bench-to-bedside translation of advanced clinical

Precision Medicine or Personalized Medicine: Fad, Myth or Here Forever?

What is Personalized Medicine (PM) and how is this new approach enabling better healthcare? Medical practitioners have always known that patients respond differently to drugs and procedures; one of the simplest examples would be allergies, for instance to peanuts or medicines.

ERG deletions: the Good mutation for Favourable prognosis in Acute Lymphoblastic Leukemia

A novel subgroup of B-cell ALL with CD2 expression that does not belong in the other defined groups has been recently discovered26,27. This subgroup harbors intragenic deletions in the ERG gene that codes for a transcription factor in hematopoiesis. It

IKZF1 (IKAROS): The Mutation that’s now most important in Acute Lymphocytic Leukemia

IKZF1 The IKZF1 gene on the short-arm of chromosome 7 codes for IKAROS, a hematopoietic transcription factor with an essential role in lymphoid differentiation. It rose to prominence in 2009 when multiple groups discovered recurrent focal deletions in its exons11,12,

DNMT3A: Why and How to test this Important Gene in Acute Myeloid Leukemia

DNMT3A codes for the enzyme DNA methyltransferase 3A that facilitates DNA methylation, thus playing a major role in epigenetic regulation of gene expression. In 2010, the first carcinogenic mutations in DNMT3A were identified1, which have since been found to occur

Why Genital Tuberculosis is an Important Issue and How to deal with it?

The burden of tuberculosis (TB) in India is the highest, accounting for one-fifth (21%) of the global incidence [1]. TB affecting organs other than the lungs is known as extrapulmonary TB (EPTB). The paucibacillary smear status and localization into sites

How to keep your Family Safe from Heart Disease and Stroke Risks

Heart Attack and Stroke Risk: Thrombophilia Blood clotting is regulated by your genes. Some people have a high propensity of clotting which can lead to high risk of developing heart attack, stroke, pulmonary embolism, or venous thrombosis. This test is

How to Stay out of the Hospital and Emergency Room for Heart disease and Stroke patients

Medicine for Thrombosis and Stroke may cause the other extreme: Bleeding emergencies on Warfarin Warfarin or Coumadin is one of the most popular drugs in the world, and the leading cause of emergency hospitalizations in the USA. This is because

Make sure that your Blood Thinners are Helping and NOT Harming you

Heart drug may cause Heart Attack or Bleeding: Clopidogrel People with heart disease and/or stroke are put on this medicine, but in the majority it leads to heart attack, which it was intended to prevent, or to bleeding emergencies. This

The Smart way to beat High Cholesterol and Heart Disease

Drug-induced Muscle Damage: Statins for Cholesterol and Diabetes Tablets are given to reduce cholesterol for people with high blood pressure or in diabetics. They can lead to muscle degradation leading to aches, pains and cramps of muscles, and eventually in