The most common blood thinner has to be given at the right dose for it to be effective and safe. Instead, if you’re taking drugs that are 100-times more expensive, you may be wasting money unnecessarily. The report will predict your risks for emergencies such as heart attack, stroke or internal bleeding when given this medicine, and advice your doctor on the safe dosage or alternative therapy.
On the other hand, those of you that can take this medicine safely may be taking other more expensive drugs. This test will guide you on switching to the cheaper generic medicine and staying healthy both in body and bank account.
Science
Genes tested: CYP2C19*2, CYP2C19*3, CYP2C19*17
Clopidogrel is metabolized in the body to its active form, and this metabolism is controlled by genes. Six out of 10 people carry a mutation either slowing down their metabolism or speeding it up considerably. This results in either inadequate drug or excess of it in blood. Both can be extremely dangerous situations leading to emergency situations such as repeat heart attack, stroke or internal bleeding.
References
Cresci S et al. 2014, Circulation and Cardiovascular Genetics
Horenstein RB et al. 2014, Journal of Clinical Pharmacology
Scott SA et al. 2013, Clinical Pharmacology and Therapeutics
Mao L et al. 2013, Archives of Cardiovascular Diseases
Zabalza M et al. 2012, Heart
