Hypothyroidism or Cancer? A simple test can Stop Thyroid Cancer before it strikes!

A 38-year old mother found she had a mutation in her thyroid nodules before it turned into cancer with Swagene’s innovative diagnostics. Hypothyroidism, characterized by high TSH (thyroid stimulating hormone) levels, is widely prevalent across the world and strikes more

Lung Cancer got a mighty enemy with Easier sampling and Quick results in 48 hours

A woman with lung cancer got EGFR mutation results in 48 hours, and tumour regression by Day 3 with Swagene’s innovations. Lung cancer (adenocarcinoma of the lung) is dominated by EGFR mutations especially in Asians. The majority of patients who

ERG deletions: the Good mutation for Favourable prognosis in Acute Lymphoblastic Leukemia

A novel subgroup of B-cell ALL with CD2 expression that does not belong in the other defined groups has been recently discovered26,27. This subgroup harbors intragenic deletions in the ERG gene that codes for a transcription factor in hematopoiesis. It

IKZF1 (IKAROS): The Mutation that’s now most important in Acute Lymphocytic Leukemia

IKZF1 The IKZF1 gene on the short-arm of chromosome 7 codes for IKAROS, a hematopoietic transcription factor with an essential role in lymphoid differentiation. It rose to prominence in 2009 when multiple groups discovered recurrent focal deletions in its exons11,12,

DNMT3A: Why and How to test this Important Gene in Acute Myeloid Leukemia

DNMT3A codes for the enzyme DNA methyltransferase 3A that facilitates DNA methylation, thus playing a major role in epigenetic regulation of gene expression. In 2010, the first carcinogenic mutations in DNMT3A were identified1, which have since been found to occur

Children with blood cancer to benefit from advanced molecular tests for IKZF1 and ERG

  Blood cancer, or leukemias, are complicated because of the large number of ‘driver’ genetic mutations seen in the disease. These mutations affect the disease in terms of severity, survival, and risk of relapse. Apart from detecting the disease and

Molecular genetic testing should be mandatory for diagnostic accuracy of Sarcoma and appropriate clinical management

Molecular diagnostics offer unparalleled sensitivity and accuracy in Sarcomas Accurate Cancers of soft tissues, sarcomas, have many different types. It can be notoriously difficult to precisely diagnose some of the sarcomas in the histopathology laboratory. It is reported that even